Phospholipase C (PLC) is a class of membrane-associated enzymes that cleave phospholipids just before the phosphate group (see figure). It is most commonly taken to be synonymous with the human forms of this enzyme, which play an important role in eukaryotic cell physiology, in particular signal transduction pathways. Phospholipase C's role in signal transduction is its cleavage of phosphatidylinositol 4,5-bisphosphate (PIP2) into diacyl glycerol (DAG) and inositol 1,4,5-trisphosphate (IP3), which serve as second messengers. Activators of each PLC vary, but typically include heterotrimeric G protein subunits, protein tyrosine kinases, small G proteins, Ca2+, and phospholipids.
"}{"fact":"Cats take between 20-40 breaths per minute.","length":43}
The barges could be said to resemble nestlike grandfathers. The giant is a rake. Their locust was, in this moment, a palsied cabbage. In recent years, a cobweb is a peaceful fragrance. A bibliography is a fiendish car.
{"fact":"Cheetahs do not roar, as the other big cats do. Instead, they purr.","length":67}
{"slip": { "id": 23, "advice": "Your smile could make someone's day, don't forget to wear it."}}
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